The Parker H. Petit Institute for Bioengineering and Bioscience at Georgia Tech

Georgia Tech The Parker H. Petit Institute for Bioengineering and Bioscience Creating Opportunities for the Future

News

  • neurons Bioscience and Engineering Converge (July 21, 2008) — Marking its 10th anniversary this year, the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University continues to build its interdisciplinary programs to tackle the challenges of the 21st century, including cardiovascular disease, nerve injuries, neurological disorders and cancer.
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  • titanium coating New Titanium Coating Improves Joint Replacements (July 1, 2008) — Research at the Georgia Institute of Technology shows that coating a titanium implant with a new biologically inspired material enhances tissue healing, improves bone growth around the implant and strengthens the attachment and integration of the implant to the bone.
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  • microchip Automated Microfluidic Device Reduces Time to Screen Small Organisms (June 23, 2008) — Genetic studies on small organisms such as worms and flies can now be done more quickly using a new microfluidic device developed by engineers at the Georgia Institute of Technology. The microchip automatically positions, images and sorts small organisms.
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  • Tech Tower Computer Predicts Anti-Cancer Molecules (June 17, 2008) — A new computer-based method of analyzing cellular activity has correctly predicted the anti-tumour activity of several molecules. Research published today in BioMed Central's open access journal, Molecular Cancer, describes 'CoMet' – a tool that studies the integrated machinery of the cell and predicts those components that will have an effect on cancer.
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  • Tech Tower Public Funding Impacts Progress of Human Embryonic Stem Cell Research (June 4, 2008) — Bolstered by supportive policies and public research dollars, the United Kingdom, Israel, China, Singapore and Australia are producing unusually large shares of human embryonic stem cell research. While states like California and New York are picking up more research funding in the U.S.
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  • embryoid bodies Molecule Delivery Method Improves Embryonic Stem Cell Differentiation (April 9, 2008) — New research shows that delivering molecules within aggregates of embryonic stem cells via biodegradable microspheres enhances the efficiency and purity of differentiation.
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  • Magnets Capture Cancer Cells (July 24, 2008) — Magnetic nanoparticles coated with a specialized targeting molecule were able to latch on to cancer cells in mice and drag them out of the body. The results are described in a study published online this month in the Journal of the American Chemical Society. The study's authors, researchers at Georgia Institute of Technology, hope that the new technique will one day provide a way to test for—and potentially even treat—metastatic ovarian cancer.
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  • Bellamkonda's Research Highlighted in Science (July 10, 2008) — Peripheral nerve regeneration across long nerve gaps is clinically challenging. Autografts, the standard of therapy, are limited by availability and other complications. Here, using rigorous anatomical and functional measures, we report that aligned polymer fiber-based constructs present topographical cues that facilitate the regeneration of peripheral nerves across long nerve gaps. Significantly, aligned but not randomly oriented fibers elicit regeneration, establishing that topographical cues can influence endogenous nerve repair mechanisms in the absence of exogenous growth promoting proteins. Axons regenerated across a 17 mm nerve gap, reinnervated muscles, and reformed neuromuscular junctions. Electrophysiological and behavioral analyses revealed that aligned but not randomly oriented constructs facilitated both sensory and motor nerve regeneration, significantly improved functional outcomes. Additionally, a quantitative comparison of DRG outgrowth in vitro and nerve regeneration in vivo on aligned and randomly oriented fiber films clearly demonstrated the significant role of sub-micron scale topographical cues in stimulating endogenous nerve repair mechanisms.


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  • Biomaterials Team Awarded NIH Training Grant (July 9, 2008) — A training grant, entitled "Graduate Training for Rationally Designed, Integrative Biomaterials" or "GTBioMAT" was awarded by the National Institutes of Health to the Georgia Tech/Emory Biomaterials Research Team. Ravi Bellamkonda, PhD, Principal Investigator and Director and Julie Babensee, PhD, Co-Director, will be responsible for the overall management and implementation of the program's objectives.

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  • Non-invasive tracking of nanocarrier distribution in tumors (July 3, 2008) — Nanocarrier-mediated chemotherapy has great promise in the treatment of cancer due to its ability to prolong the blood plasma half-life of the encapsulated chemotherapeutic and to selectively accumulate in tumors. However, in spite of important advances in the development of nano-chemotherapeutics, systemic chemotherapy is not the treatment of choice for malignant brain tumors, primarily due to the toxicity caused to non-tumor tissue. Therefore, novel techniques are required to understand and improve the drug availability at the tumor site while reducing harmful side effects. Nano-chemotherapeutics are able to accumulate at the tumor lesion due to the prolonged circulation of the nanocarrier and presence of abnormal leaky vasculature at the tumor site via the enhanced permeation and retention effect (EPR).
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  • Todd McDevitt's Research Highlighted on Live Science (May 23, 2008) — Behind the Scenes: Stem Cell Research Goes Beyond Biology
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  • LaPlaca and Wright Honored as "Healthcare Heroes" for DETECT Device (May 9, 2008) — Georgia team works on early DETECTion of Alzheimer's
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HILTON HEAD WORKSHOP

Every year in March, IBB sponsors a weekend workshop that brings together...
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SUDDATH SYMPOSIUM

The Suddath Symposium is held annually to celebrate Bud Suddath's life and discuss the latest developments in a timely field of bioengineering and bioscience.

Learn more at the Suddath Symposium Web site.